DIPEPTIDYL PEPTIDASE IV INHIBITOR-ASSOCIATED BULLOUS PEMPHIGOID: A RECENTLY RECOGNIZED AUTOIMMUNE BLISTERING DISEASE WITH UNIQUE CLINICAL, IMMUNOLOGICAL AND GENETIC CHARACTERISTICS

Bullous pemphigoid (BP) is an organ-specific autoantibody-mediated autoimmune blistering skin disorder that tends to affect the elderly.Tense blister formation associated with itchy urticarial erythema is clinically observed in BP, and subepidermal blister formation with eosinophilic infiltration is a histopathological characteristic.BP autoantibod

It is now well-established that microRNAs (miRNAs) are important regulators of gene expression.The role of miRNAs in placental development and trophoblast function is constantly expanding.Trophoblast invasion and their ability to remodel uterine spiral arteries are essential for proper placental development and successful pregnancy outcome.Many miR

Abstract Background The diabetogenic action of statins remains a concern, particularly in patients at high risk for diabetes receiving intensive statin therapy.Despite the risk of diabetes with statin use being considered a potential class effect, recent studies have suggested that pitavastatin exerts neutral or favorable effects on diabetogenicity

Objectives: This study investigated how different concentrations of doxorubicin (DOX) can affect the function of cardiac cells.This study also examined whether activation of prokineticin receptor (PKR)-1 by a nonpeptide agonist, IS20, prevents DOX-induced cardiovascular toxicity in mouse models.Background: High prevalence of heart failure during an

The tarnished plant bug, Lygus lineolaris (Hemiptera: Miridae), has a wide host range of over 700 plant species, including Picnic Sets 130 crops of economic importance.During early spring, managing the field edges with weeds and other wild hosts is important in preventing early-season infestations of L.lineolaris in cotton to prevent damage to the